New drug interaction study launches for polycystic kidney disease treatment

NCT ID NCT07565441

Not yet recruiting Knowledge-focused Sponsor: Jemincare Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage study tests how a new drug called JMKX003142 interacts with other common medications in 112 healthy Chinese adults. The drug is being developed for autosomal dominant polycystic kidney disease (ADPKD). Researchers will measure how the body processes JMKX003142 when taken with drugs like fluconazole, cyclosporine, and omeprazole. The results will help determine safe dosing for future patient studies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JMKX003142 tablets

What this could lead to

If successful, this study will show how JMKX003142 interacts with other drugs, helping doctors choose safe doses for future ADPKD patients.

What could go wrong

This is an early Phase 1 trial in healthy people, not patients. It only checks drug interactions, not whether JMKX003142 works for ADPKD. Results may not predict real-world effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal dominant polycystic kidney disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.