New Clot-Busting catheter shows promise in leg vein blockages

NCT ID NCT07027878

Completed Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how well the JETi device works in real-world settings to remove blood clots from deep leg veins (venous thrombosis). The device uses suction and tiny water jets to break up and remove clots. In 121 patients, the device successfully cleared at least 75% of the clot in most cases, with few serious complications like bleeding or re-clotting within 30 days. The results suggest the JETi system is a safe and effective tool for treating acute and subacute leg vein clots.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: JETi System (a catheter device that uses suction and saline jets to break up and remove blood clots)
What this could lead to: If successful, this registry could confirm that the JETi device is a safe and effective tool for quickly clearing blood clots from deep leg veins, potentially reducing long-term complications like swelling or pain.
What could go wrong: This is an observational registry, not a randomized trial, so results may be influenced by patient selection. The study is also relatively small (121 participants) and lacks a comparison group, making it hard to prove the device is better than other treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

thrombophilia due to thrombin defect venous thromboembolism Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENOUS THROMBOSIS

Contacts and locations

Locations

Arkansas Heart Hospital

Little Rock, Arkansas, 72211, United States
Ascension St. John Jane Phillips

Bartlesville, Oklahoma, 74006, United States
Cedars Sinai Medical Center

Los Angeles, California, 90095, United States
Charleston Area Medical Center

Charleston, West Virginia, 25304, United States
ClinRé

Thornton, Colorado, 80023, United States
Evangelisches Krankenhaus Königin Elisabeth Herzberge

Berlin, 10365, Germany
Hendrick Medical Center

Abilene, Texas, 79601, United States
Henry Ford Detroit

Detroit, Michigan, 48202, United States
Hightower Clinical

Oklahoma City, Oklahoma, 73102, United States
HonorHealth

Scottsdale, Arizona, 85258, United States
Hôpital Saint-François d'Assise

Québec, Quebec, G1L 3L5, Canada
Klinikum Hochsauerland

Arnsberg, 59759, Germany
Marien Hospital Herne

Herne, North Rhine-Westphalia, 44625, Germany
Medizinische Einrichtungen der Universität zu Köln

Cologne, 50937, Germany
Midwest Cardiovascular Research Foundation

Davenport, Iowa, 52803, United States
Mount Sinai Hospital

New York, New York, 10029, United States
PIH Good Samaritan

Los Angeles, California, 90017, United States
Royal Perth Hospital

Perth, 6000, Australia
Sankt Gertrauden Krankenhaus

Berlin, 10713, Germany
Southoast Hospital

Fall River, Massachusetts, 02740, United States
St. Luke's Hospital

Kansas City, Missouri, 64111, United States
St. Mary Medical Center

Hobart, Indiana, 46342, United States
Stanford University Hospital and Clinics

Palo Alto, California, 94305, United States
University Hospital Aachen

Aachen, North Rhine-Westphalia, 52074, Germany
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44195, United States
University of Colorado

Aurora, Colorado, 80045, United States
University of Louisville

Louisville, Kentucky, 40202, United States
University of Utah Hospital

Salt Lake City, Utah, 84132, United States
Universitätsklinikum Giessen

Giessen, 35392, Germany
Weill Cornell Medicine

New York, New York, 10021, United States

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