Experimental drug shows promise for rare, deadly brain disease

NCT ID NCT05998395

First seen Feb 03, 2026 · Last updated May 14, 2026 · Updated 15 times

Summary

This study tested a drug called ruxolitinib in one adult with Kohlmeier-Degos disease affecting the brain and spinal cord. The goal was to see if the drug could stop new lesions from forming or shrink existing ones. The participant took the drug twice daily for up to 26 weeks and had regular MRI scans and other tests to monitor effects.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.