Could a common arthritis drug tame a rare, fatal blood vessel disease?
NCT ID NCT06923072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether baricitinib, a drug already approved for arthritis, can help people with Kohlmeier-Degos (KD) disease that affects the brain and spine. KD causes inflammation and blood clots that damage small blood vessels, and there is currently no treatment. The trial will enroll 12 adults who will take baricitinib daily for 24 weeks, and researchers will use MRI scans to see if existing lesions stabilize and no new ones appear.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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