Jail-Based injection could help opioid patients stay on treatment after release
NCT ID NCT06051890
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 27 times
Summary
This study tests whether starting a monthly buprenorphine injection (Sublocade) in jail helps people with opioid use disorder stay on treatment after release. Two hundred men entering jail with a sublingual buprenorphine prescription will be randomly assigned to either switch to the injection or stay on the daily tablet. The main goal is to see if more people leave jail with at least a week of buprenorphine in their system and continue treatment in the community.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baystate Health
RECRUITINGSpringfield, Massachusetts, 01199, United States
Contact
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Middlesex County House of Corrections
RECRUITINGNew Brunswick, New Jersey, 08902, United States
Contact Phone: •••-•••-••••
Contact
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NYU Langone Health - 180 Madison Ave
RECRUITINGNew York, New York, 10016, United States
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Tufts University Health Sciences
RECRUITINGBoston, Massachusetts, 02111, United States
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Extended-release buprenorphine (Sublocade injection)
What this could lead to
If it works, this could show that starting long-acting buprenorphine in jail helps more people stay on treatment after release, reducing relapse and overdose risk.
What could go wrong
This is a single-site trial with 200 men, so results may not apply to everyone. The intervention requires stable use of sublingual buprenorphine first, which limits who can join.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.