New drug aims to slow vision loss in Age-Related blindness
NCT ID NCT06769048
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a drug called BI 1584862 in 150 adults aged 50+ with geographic atrophy, an advanced form of age-related macular degeneration that causes blind spots. Participants receive either the drug or a placebo for 1 year. Doctors track changes in the retina using special imaging to see if the drug slows the growth of damaged areas.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BI 1584862
- What this could lead to
- If it works, this could point toward a treatment to slow vision loss from geographic atrophy, a leading cause of blindness.
- What could go wrong
- This is an early Phase 2 trial with only 150 people. The drug may not slow the disease or could have side effects. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Associated Retina Consultants
Gilbert, Arizona, 85297, United States
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Associated Retina Consultants, Ltd.
Phoenix, Arizona, 85020, United States
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Austin Clinical Research, LLC
Austin, Texas, 78750, United States
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Bay Area Retina Associates - Walnut Creek
Walnut Creek, California, 94598, United States
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Cameron Ria, LLC
Phoenix, Arizona, 85050, United States
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Center for Retina and Macular Disease
Winter Haven, Florida, 33880, United States
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Charleston Neuroscience Institute - Charleston
Charleston, South Carolina, 29414, United States
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Coastal Eye Surgeons
Greenwich, Connecticut, 06830, United States
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Cumberland Valley Retina Consultants
Hagerstown, Maryland, 21740, United States
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East Florida Eye Institute
Stuart, Florida, 34994, United States
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Emanuelli Research & Development Center
Arecibo, 00612, Puerto Rico
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Emerson Clinical Research Institute
Falls Church, Virginia, 22042, United States
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Eye Associates of Pinellas
Pinellas Park, Florida, 33782, United States
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Eye Research Foundation
Newport Beach, California, 92663, United States
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EyeHealth Northwest
Portland, Oregon, 97225, United States
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Global Research Management
Glendale, California, 91204, United States
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Illinois Retina Associates - Oak Park
Oak Park, Illinois, 60304, United States
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MedEye Associates
Miami, Florida, 33143, United States
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Mid Atlantic Retina
Philadelphia, Pennsylvania, 19107, United States
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NJRetina
Teaneck, New Jersey, 07666, United States
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Northern California Retina Vitreous Associates MedicalGroup, Inc.
Mountain View, California, 94040, United States
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Ophthalmic Consultants of Boston
Boston, Massachusetts, 02114, United States
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Pacific Northwest Retina
Bellevue, Washington, 98004, United States
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Piedmont Eye Center
Lynchburg, Virginia, 24502, United States
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Red River Research Partners, LLC - Plano
Plano, Texas, 75024, United States
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Retina Associates of Southern California
Huntington Beach, California, 92647, United States
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Retina Consultants of San Diego
Poway, California, 92064, United States
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Retina Consultants of Texas - Schertz
Schertz, Texas, 78154, United States
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Retina Consultants of Texas-Beaumont-70319
Beaumont, Texas, 77707, United States
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Retina Consultants of Texas-The Woodlands-67575
The Woodlands, Texas, 77384, United States
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Retina Foundation of the Southwest
Dallas, Texas, 75231, United States
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Retina Macula Institute of Arizona
Scottsdale, Arizona, 85255, United States
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Retina Northwest
Portland, Oregon, 97221, United States
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Retina Specialists of Colorado Research, LLC
Denver, Colorado, 80222, United States
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Retina-Vitreous Associates Medical Group
Beverly Hills, California, 90211, United States
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Retinal Consultants Medical Group
Sacramento, California, 95825, United States
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Retinal Consultants Medical Group, Inc
Modesto, California, 95356, United States
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Retinal Consultants of San Antonio
San Antonio, Texas, 78240, United States
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Southeast Retina Center, PC
Augusta, Georgia, 30909, United States
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Tennessee Retina
Nashville, Tennessee, 37203, United States
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The Eye Care Institute
Louisville, Kentucky, 40206, United States
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University of Missouri Health System
Columbia, Missouri, 65212, United States
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Verum Research, LLC
Eugene, Oregon, 97401, United States
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Vitreo Retinal Associates - Gainesville
Gainesville, Florida, 32605, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Gene therapy injection aims to halt blinding eye disease
- Eye imaging showdown: which device measures macular damage best?
- Bionic eye implant aims to bring back sight in advanced macular degeneration
- New cell therapy aims to slow vision loss in retinal disease
- New pill aims to slow vision loss from dry macular degeneration
- Gene therapy injection aims to halt blinding eye disease