New pill targets hard-to-treat cancers with rare mutation
NCT ID NCT06386146
First seen Jan 28, 2026 · Last updated Jun 10, 2026 · Updated 19 times
Summary
This study tests an experimental drug called JAB-30355 in adults with advanced solid tumors that have a specific TP53 Y220C mutation. The goal is to see if the drug is safe, tolerable, and shows signs of shrinking tumors. About 144 participants will receive the drug, and researchers will monitor side effects and how the drug moves through the body.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site
RECRUITINGDenver, Colorado, 80218, United States
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Research Site
RECRUITINGNashville, Tennessee, 37203, United States
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Research Site
RECRUITINGBeijing, Beijing Municipality, 100000, China
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Research Site
RECRUITINGBeijing, Beijing Municipality, 100021, China
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Research Site
RECRUITINGBeijing, Beijing Municipality, 100142, China
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Research Site
RECRUITINGGuangzhou, Guangdong, 510000, China
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Research Site
RECRUITINGZhengzhou, Henan, 451191, China
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Research Site
RECRUITINGShenyang, Liaoning, 110801, China
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Research Site
RECRUITINGJinan, Shandong, 250117, China
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Research Site
RECRUITINGShanghai, Shanghai Municipality, 200032, China
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Research site
TERMINATEDLake Mary, Florida, 32771, United States
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Research site
RECRUITINGSt Louis, Missouri, 63110, United States
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Research site
TERMINATEDCanton, Ohio, 44718, United States
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Research site
RECRUITINGCleveland, Ohio, 44195, United States
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Research site
RECRUITINGHouston, Texas, 77030, United States
Conditions
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