New targeted drug hopes to shrink Hard-to-Treat tumors
NCT ID NCT06386146
First seen Jan 28, 2026 · Last updated Apr 28, 2026 · Updated 9 times
Summary
This study tests an experimental drug called JAB-30355 in adults with advanced solid tumors that have a specific mutation in the TP53 gene (Y220C). The goal is to see if the drug is safe, tolerable, and can shrink tumors. About 144 participants who have already tried at least one other cancer treatment will receive the drug, and researchers will monitor side effects and measure drug levels in the blood.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site
RECRUITINGDenver, Colorado, 80218, United States
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Research Site
RECRUITINGNashville, Tennessee, 37203, United States
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Research Site
RECRUITINGBeijing, Beijing Municipality, 100000, China
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Research Site
RECRUITINGBeijing, Beijing Municipality, 100021, China
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Research Site
RECRUITINGBeijing, Beijing Municipality, 100142, China
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Research Site
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510000, China
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Research Site
NOT_YET_RECRUITINGJinan, Shandong, 250117, China
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Research Site
RECRUITINGShanghai, Shanghai Municipality, 200032, China
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Research site
RECRUITINGLake Mary, Florida, 32771, United States
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Research site
RECRUITINGSt Louis, Missouri, 63110, United States
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Research site
TERMINATEDCanton, Ohio, 44718, United States
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Research site
RECRUITINGCleveland, Ohio, 44195, United States
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Research site
RECRUITINGHouston, Texas, 77030, United States
Conditions
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