New oral cocktail aims to tame myeloma with fewer side effects

NCT ID NCT02412228

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This phase 2 study tested a combination of three oral drugs (ixazomib, cyclophosphamide, and dexamethasone) as the first treatment for multiple myeloma in 12 newly diagnosed patients. The goal was to see if this all-oral regimen could control the disease effectively while causing less nerve damage than older treatments. The study measured how many patients responded and what side effects occurred.

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Contacts and locations

Locations

  • Memorial Hospital of Rhode Island

    Pawtucket, Rhode Island, 02860, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

Conditions

Explore the condition pages connected to this study.