Experimental chemo drug tested for advanced breast cancer

NCT ID NCT04796324

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tested the chemotherapy drug ixabepilone in 13 patients with metastatic breast cancer that had stopped responding to standard treatments. The goal was to see if the drug could shrink tumors or slow the disease. The study was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ixabepilone (a chemotherapy drug)
What this could lead to
If successful, this could provide a treatment option for metastatic breast cancer patients who have not responded to standard chemotherapies.
What could go wrong
This was a small, early-phase trial that was terminated, so results are limited. Ixabepilone may not work for all patients and can cause side effects like nerve damage and low blood cell counts.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Antwerp University Hospital

    Antwerp, Edegem, 2650, Belgium

  • Beatson West of Scotland Cancer Centre

    Glasgow, Scotland, G12 0YN, United Kingdom

  • CHU de Liege, Oncology Department

    Liège, 4000, Belgium

  • Cancer Institute Singleton Hospital

    Swansea, Wales, SA2 8QA, United Kingdom

  • Centrum Onkologii Ziemi Lubelskiej im.

    Lublin, 20-090, Poland

  • Charité - Universitätsmedizin Berlin

    Berlin, 10117, Germany

  • Clin. Univ. Saint-Luc

    Brussels, 1200, Belgium

  • Edinburgh Cancer Centre, Western General Hospital

    Edinburgh, EH4 2XR, United Kingdom

  • Ikazia Hospital Rotterdam

    Rotterdam, 3083, Netherlands

  • Medway NHS Foundation Trust

    Gillingham, Kent, ME7 5NY, United Kingdom

  • Modena University Hospital

    Modena, 41124, Italy

  • Nottingham University Hospitals

    Nottingham, Nottingham, NG5 1PB, United Kingdom

  • Oddział Onkologii Klinicznej, Szpital Kliniczny Przemienienia Pańskiego UM w Poznaniu

    Poznan, 61-848, Poland

  • Onze-Lieve-Vrouwziekenhuis

    Aalst, Aalst, 9300, Belgium

  • Somerset NHS Foundation Trust

    Taunton, Somerset, TA1 5DA, United Kingdom

  • St James Hospital

    Leeds, LS9 7TF, United Kingdom

  • Tampere University Hospital

    Tampere, Pirkanmaa, 33520, Finland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, 80-214, Poland

  • Wojewodzki Szpital Specjalietyczny

    Biała Podlaska, Biala Podlaska, 21-500, Poland

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