Cancer drug trial halted early: ixabepilone fails to show promise in advanced breast cancer

NCT ID NCT04796324

First seen Mar 14, 2026 · Last updated May 10, 2026 · Updated 7 times

Summary

This study tested the chemotherapy drug ixabepilone in 13 people with advanced or metastatic breast cancer whose disease had stopped responding to two common types of chemotherapy (anthracyclines and taxanes). The goal was to see if the drug could shrink tumors or slow the cancer. However, the trial was terminated early, meaning it did not meet its goals or was stopped for other reasons.

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Contacts and locations

Locations

  • Antwerp University Hospital

    Antwerp, Edegem, 2650, Belgium

  • Beatson West of Scotland Cancer Centre

    Glasgow, Scotland, G12 0YN, United Kingdom

  • CHU de Liege, Oncology Department

    Liège, 4000, Belgium

  • Cancer Institute Singleton Hospital

    Swansea, Wales, SA2 8QA, United Kingdom

  • Centrum Onkologii Ziemi Lubelskiej im.

    Lublin, 20-090, Poland

  • Charité - Universitätsmedizin Berlin

    Berlin, 10117, Germany

  • Clin. Univ. Saint-Luc

    Brussels, 1200, Belgium

  • Edinburgh Cancer Centre, Western General Hospital

    Edinburgh, EH4 2XR, United Kingdom

  • Ikazia Hospital Rotterdam

    Rotterdam, 3083, Netherlands

  • Medway NHS Foundation Trust

    Gillingham, Kent, ME7 5NY, United Kingdom

  • Modena University Hospital

    Modena, 41124, Italy

  • Nottingham University Hospitals

    Nottingham, Nottingham, NG5 1PB, United Kingdom

  • Oddział Onkologii Klinicznej, Szpital Kliniczny Przemienienia Pańskiego UM w Poznaniu

    Poznan, 61-848, Poland

  • Onze-Lieve-Vrouwziekenhuis

    Aalst, Aalst, 9300, Belgium

  • Somerset NHS Foundation Trust

    Taunton, Somerset, TA1 5DA, United Kingdom

  • St James Hospital

    Leeds, LS9 7TF, United Kingdom

  • Tampere University Hospital

    Tampere, Pirkanmaa, 33520, Finland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, 80-214, Poland

  • Wojewodzki Szpital Specjalietyczny

    Biała Podlaska, Biala Podlaska, 21-500, Poland

Conditions

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