New targeted pill shows promise for rare bile duct cancer in Real-World study

NCT ID NCT06607302

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is tracking 100 adults with a rare and aggressive bile duct cancer that has a specific IDH1 gene mutation. Participants will take the targeted drug ivosidenib, which was recently approved in Europe. Researchers will monitor how long the cancer stays under control, overall survival, and quality of life in everyday medical practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ivosidenib (a targeted cancer pill)

What this could lead to

If successful, this study could confirm that ivosidenib is a safe and effective treatment option for people with this rare bile duct cancer, potentially improving survival and quality of life.

What could go wrong

This is an observational study, not a controlled trial, so results may be less definitive. The cancer is aggressive, and the drug may not work for everyone or may cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Caritas Krankenhaus Bad Mergentheim

    RECRUITING

    Bad Mergentheim, Germany

    Contact

  • Gemeinschaftspraxis Hämatologie - Onkologie

    RECRUITING

    Dresden, Germany

    Contact

  • Gemeinschaftspraxis für Internistische Onkologie und Hämatologie

    RECRUITING

    Rheine, Germany

    Contact

  • Hämatologisch-Onkologische Schwerpunktpraxis in Bad Liebenwerda

    RECRUITING

    Bad Liebenwerda, Germany

    Contact

  • Medizinisches Versorgungszentrum Mönchengladbach

    RECRUITING

    Mönchengladbach, Germany

    Contact

  • Onkologie Hannover

    RECRUITING

    Hanover, Germany

    Contact

  • Onkologie Hof

    RECRUITING

    Hof, Germany

    Contact

  • Onkologisches Versorgungszentrum Berlin MVZ

    RECRUITING

    Berlin, Germany

    Contact

  • Onkozentrum Dresden

    RECRUITING

    Dresden, Germany

    Contact

  • RoMed Klinikum Rosenheim, Hämatologie und Onkologie

    RECRUITING

    Rosenheim, Germany

    Contact

  • TUM Klinikum Rechts der Isar, Klinik und Poliklinik für Innere Medizin II

    RECRUITING

    München, Germany

    Contact

  • Universitätsklinikum Essen, Innere Klinik (Tumorforschung)

    RECRUITING

    Essen, Germany

    Contact

  • ze:roPRAXEN MVZ für Innere Medizin

    RECRUITING

    Weinheim, Germany

    Contact