New hope for mesothelioma: drug targets cancer from two angles
NCT ID NCT06840834
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This phase 2 trial tests a drug called ivonescimab in 38 people with pleural mesothelioma whose cancer has returned after immunotherapy and chemotherapy. The drug works by blocking blood vessel growth and boosting the immune system to fight cancer. The main goal is to see if the drug can stop the cancer from growing for at least 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ivonescimab (a drug that targets blood vessel growth and the immune system)
- What this could lead to
- If successful, this could offer a new treatment option for patients with pleural mesothelioma whose cancer has returned after standard therapies.
- What could go wrong
- This is a small, early-phase trial with only 38 participants, so results may not apply to everyone. The drug may cause side effects or fail to control the disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Besançon - CHU
RECRUITINGBesançon, France
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Bordeaux - CHU
RECRUITINGPessac, France
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Brest - CHU
RECRUITINGBrest, France
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Caen - CHU
RECRUITINGCaen, France
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Centre Leon Berard
NOT_YET_RECRUITINGLyon, France
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Clermont-Ferrand - Centre Jean Perrin
RECRUITINGClermont-Ferrand, France
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Créteil - CHI
RECRUITINGCréteil, France
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Grenoble - CHU
RECRUITINGGrenoble, France
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Le Mans - CHG
RECRUITINGLe Mans, France
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Lille - CHU
RECRUITINGLille, France
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Lyon - HCL
RECRUITINGPierre-Bénite, France
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Marseille - APHM
RECRUITINGMarseille, France
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Metz - Hôpital Robert Schuman
RECRUITINGVantoux, France
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Montpellier - CHU
RECRUITINGMontpellier, France
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Mulhouse - GHRMSA
RECRUITINGMulhouse, France
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Nantes - Hôpital Laennec
RECRUITINGNantes, France
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Paris - Bichat
RECRUITINGParis, France
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Strasbourg - Nouvel Hôpital Civil
RECRUITINGStrasbourg, France
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Toulon - CHI
RECRUITINGToulon, France
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Toulouse - CHU
RECRUITINGToulouse, France
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Tours - CHU
RECRUITINGTours, France
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