Old drug, new hope? ivermectin shows promise for PKDL in small trial

NCT ID NCT06251739

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 33 times

Summary

This early study tested whether a common anti-parasite drug, ivermectin, could safely treat PKDL, a skin condition that can develop after kala-azar. Thirty adults in Bangladesh received either ivermectin or the standard treatment miltefosine. The goal was to see if ivermectin could clear the parasite and reduce skin lesions with fewer side effects. Results suggest ivermectin is safe and may offer a shorter, simpler treatment option.

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Contacts and locations

Locations

  • International Centre for Diarrhoeal Disease Research, Bangladesh

    Dhaka, Dhaka Division, 1212, Bangladesh

Conditions

Explore the condition pages connected to this study.