Old drug, new hope? ivermectin shows promise for PKDL in small study

NCT ID NCT07286604

First seen Dec 26, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This early study tested the safety and effectiveness of the drug ivermectin for treating post-kala-azar dermal leishmaniasis (PKDL), a skin condition that can develop after recovery from visceral leishmaniasis. Ten otherwise healthy adults with PKDL took ivermectin pills for five days each month for three months. The study found no severe side effects and all participants had negative skin tests for the parasite after treatment, suggesting ivermectin may be a safe and convenient option for PKDL.

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Contacts and locations

Locations

  • International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)

    Dhaka, 1212, Bangladesh

Conditions

Explore the condition pages connected to this study.