New injection tested for stubborn sinus polyps

NCT ID NCT06834360

Summary

This study is testing an investigational injectable medication called itepekimab for adults whose chronic sinusitis with nasal polyps is not well-controlled by standard nasal steroid sprays. Over 52 weeks, researchers will compare two dosing schedules of itepekimab against a placebo to see if it reduces polyp size and symptoms like congestion and loss of smell. The goal is to see if this new treatment can better control the disease and potentially reduce the need for oral steroids or surgery.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced ENT & Allergy - Louisville- Site Number : 8400007

    RECRUITING

    Louisville, Kentucky, 40220, United States

  • Advanced Research Institute - New Port Richey- Site Number : 8400014

    RECRUITING

    New Port Richey, Florida, 34653, United States

  • Allergy, Asthma and Clinical Research- Site Number : 8400002

    RECRUITING

    Oklahoma City, Oklahoma, 73120, United States

  • Cedars-Sinai Medical Center- Site Number : 8400030

    RECRUITING

    Los Angeles, California, 90048, United States

  • Centro de Pesquisa Clínica de Marília - CPCLIM- Site Number : 0760002

    RECRUITING

    Marília, São Paulo, 17504-072, Brazil

  • Clinica de Alergia Martti Antila- Site Number : 0760003

    RECRUITING

    Sorocaba, São Paulo, 18040-425, Brazil

  • Ear and Sinus Institute- Site Number : 8400048

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • Excel ENT of Alabama- Site Number : 8400052

    RECRUITING

    Birmingham, Alabama, 35244, United States

  • Fundação Faculdade Regional de Medicina de São José do Rio Preto- Site Number : 0760005

    RECRUITING

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • Investigational Site Number : 0320001

    RECRUITING

    Buenos Aires, 1414, Argentina

  • Investigational Site Number : 0320002

    RECRUITING

    Buenos Aires, 1121, Argentina

  • Investigational Site Number : 0320003

    RECRUITING

    Mendoza, 5500, Argentina

  • Investigational Site Number : 0320004

    RECRUITING

    Corrientes, 3400, Argentina

  • Investigational Site Number : 0320005

    RECRUITING

    San Miguel de Tucumán, Tucumán Province, 4000, Argentina

  • Investigational Site Number : 0360001

    RECRUITING

    Spearwood, Western Australia, 6163, Australia

  • Investigational Site Number : 0360002

    RECRUITING

    Brisbane, Queensland, 4029, Australia

  • Investigational Site Number : 0360003

    RECRUITING

    Bella Vista, New South Wales, 2153, Australia

  • Investigational Site Number : 0560001

    RECRUITING

    Leuven, 3000, Belgium

  • Investigational Site Number : 0560002

    RECRUITING

    Ghent, 9000, Belgium

  • Investigational Site Number : 0560004

    RECRUITING

    Gesves, Namur, 5340, Belgium

  • Investigational Site Number : 0560006

    RECRUITING

    Alken, 3570, Belgium

  • Investigational Site Number : 1240003

    RECRUITING

    Québec, Quebec, G1V 4W2, Canada

  • Investigational Site Number : 1240012

    RECRUITING

    Québec, Quebec, G2J 0C4, Canada

  • Investigational Site Number : 1240014

    RECRUITING

    Ottawa, Ontario, K1G 6C6, Canada

  • Investigational Site Number : 1240015

    RECRUITING

    Cambridge, Ontario, N1R 8L4, Canada

  • Investigational Site Number : 1240017

    RECRUITING

    Vancouver, British Columbia, V6A 2W1, Canada

  • Investigational Site Number : 1520001

    RECRUITING

    Concepción, Región del Biobío, 4070094, Chile

  • Investigational Site Number : 1520002

    RECRUITING

    Quillota, Región de Valparaíso, 2260877, Chile

  • Investigational Site Number : 1520003

    RECRUITING

    Santiago, Reg Metropolitana de Santiago, 7500505, Chile

  • Investigational Site Number : 1520004

    RECRUITING

    Talcahuano, Región del Biobío, 2687000, Chile

  • Investigational Site Number : 1560001

    RECRUITING

    Beijing, 100730, China

  • Investigational Site Number : 1560002

    RECRUITING

    Jinan, 250022, China

  • Investigational Site Number : 1560003

    RECRUITING

    Yantai, 264001, China

  • Investigational Site Number : 1560004

    RECRUITING

    Chengdu, 610017, China

  • Investigational Site Number : 1560005

    RECRUITING

    Hefei, 230001, China

  • Investigational Site Number : 1560006

    RECRUITING

    Shenyang, 110004, China

  • Investigational Site Number : 1560009

    RECRUITING

    Zibo, 255036, China

  • Investigational Site Number : 1560012

    RECRUITING

    Jingzhou, 434020, China

  • Investigational Site Number : 1560014

    RECRUITING

    Wuhan, 430060, China

  • Investigational Site Number : 1560017

    RECRUITING

    Taiyuan, 030001, China

  • Investigational Site Number : 1560019

    RECRUITING

    Hangzhou, 310003, China

  • Investigational Site Number : 1560020

    RECRUITING

    Baotou, 014040, China

  • Investigational Site Number : 1560021

    RECRUITING

    Nanning, 530021, China

  • Investigational Site Number : 1560023

    RECRUITING

    Taiyuan, 030001, China

  • Investigational Site Number : 1560024

    RECRUITING

    Suzhou, 215006, China

  • Investigational Site Number : 1560025

    RECRUITING

    Chongqing, 400016, China

  • Investigational Site Number : 2030001

    RECRUITING

    Prague, 150 06, Czechia

  • Investigational Site Number : 2030002

    RECRUITING

    Hradec Králové, 500 05, Czechia

  • Investigational Site Number : 2030003

    RECRUITING

    Pardubice, 532 03, Czechia

  • Investigational Site Number : 2030004

    RECRUITING

    Prague, 100 34, Czechia

  • Investigational Site Number : 2030005

    RECRUITING

    Pilsen, 305 99, Czechia

  • Investigational Site Number : 2080001

    RECRUITING

    Aarhus, 8200, Denmark

  • Investigational Site Number : 2080002

    RECRUITING

    Køge, 4600, Denmark

  • Investigational Site Number : 2080004

    RECRUITING

    Copenhagen, 2100, Denmark

  • Investigational Site Number : 2500001

    RECRUITING

    Nantes, 44093, France

  • Investigational Site Number : 2500004

    RECRUITING

    Marseille, 13005, France

  • Investigational Site Number : 2500005

    RECRUITING

    Toyama, 939-2716, Japan

  • Investigational Site Number : 2500007

    RECRUITING

    Toulouse, 31059, France

  • Investigational Site Number : 2500010

    RECRUITING

    Poitiers, 86021, France

  • Investigational Site Number : 2500011

    RECRUITING

    Bordeaux, 33076, France

  • Investigational Site Number : 2500014

    RECRUITING

    Pontoise, 95300, France

  • Investigational Site Number : 2760001

    RECRUITING

    Dresden, 01307, Germany

  • Investigational Site Number : 2760002

    RECRUITING

    Leipzig, 04103, Germany

  • Investigational Site Number : 3480001

    RECRUITING

    Szeged, 6720, Hungary

  • Investigational Site Number : 3480005

    RECRUITING

    Budapest, 1026, Hungary

  • Investigational Site Number : 3760001

    RECRUITING

    Nahariya, 2210001, Israel

  • Investigational Site Number : 3760002

    RECRUITING

    Rehovot, 7610001, Israel

  • Investigational Site Number : 3760003

    RECRUITING

    Haifa, 3104802, Israel

  • Investigational Site Number : 3760004

    RECRUITING

    Jerusalem, 9112001, Israel

  • Investigational Site Number : 3800001

    RECRUITING

    Milan, Milano, 20132, Italy

  • Investigational Site Number : 3800003

    RECRUITING

    Catania, 95123, Italy

  • Investigational Site Number : 3800005

    RECRUITING

    Naples, Napoli, 80131, Italy

  • Investigational Site Number : 4840001

    RECRUITING

    Guadalajara, Jalisco, 44100, Mexico

  • Investigational Site Number : 5280001

    RECRUITING

    Utrecht, 3584 CX, Netherlands

  • Investigational Site Number : 5280002

    RECRUITING

    Amsterdam, 1081 HV, Netherlands

  • Investigational Site Number : 6160001

    RECRUITING

    Bielsko-Biala, Silesian Voivodeship, 43-300, Poland

  • Investigational Site Number : 6160002

    RECRUITING

    Lodz, Lódzkie, 90-302, Poland

  • Investigational Site Number : 6160004

    RECRUITING

    Poznan, Greater Poland Voivodeship, 60-693, Poland

  • Investigational Site Number : 6160005

    RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 50-750, Poland

  • Investigational Site Number : 6420001

    RECRUITING

    Bucharest, 022328, Romania

  • Investigational Site Number : 6420002

    RECRUITING

    Brasov, 500283, Romania

  • Investigational Site Number : 6420003

    RECRUITING

    Brasov, 500091, Romania

  • Investigational Site Number : 7240002

    RECRUITING

    Santander, Cantabria, 39008, Spain

  • Investigational Site Number : 7240004

    RECRUITING

    L'Hospitalet de Llobregat, Catalunya [Cataluña], 08907, Spain

  • Investigational Site Number : 7240006

    RECRUITING

    Barcelona, Barcelona [Barcelona], 08003, Spain

  • Investigational Site Number : 7240008

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Investigational Site Number : 7240010

    RECRUITING

    Madrid, 28034, Spain

  • Investigational Site Number : 7240012

    RECRUITING

    Madrid, 28040, Spain

  • Investigational Site Number : 7920001

    RECRUITING

    Bursa, 16059, Turkey (Türkiye)

  • Investigational Site Number : 7920002

    RECRUITING

    Istanbul, 34360, Turkey (Türkiye)

  • Investigational Site Number : 7920003

    RECRUITING

    Ankara, 06230, Turkey (Türkiye)

  • Investigational Site Number : 8260001

    RECRUITING

    London, London, City of, W2 1NY, United Kingdom

  • Investigational Site Number : 8260002

    RECRUITING

    Wigan, Lancashire, WN6 9EP, United Kingdom

  • Investigational Site Number : 8260003

    RECRUITING

    Taunton, Somerset, TA1 5DA, United Kingdom

  • Johns Hopkins Hospital- Site Number : 8400017

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • One of a Kind CLinical Research Center- Site Number : 8400034

    RECRUITING

    Napa, California, 94558, United States

  • Private Practice - Dr. Nelson Rosário- Site Number : 0760001

    RECRUITING

    Curitiba, Paraná, 80810-100, Brazil

  • Spartanburg-Greer ENT & Allergy- Site Number : 8400039

    RECRUITING

    Greer, South Carolina, 29650, United States

  • Thomas Jefferson University Hospital- Site Number : 8400044

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • University of Cincinnati Medical Center- Site Number : 8400022

    RECRUITING

    Cincinnati, Ohio, 45219, United States

  • University of Florida - Jacksonville- Site Number : 8400053

    RECRUITING

    Jacksonville, Florida, 32209, United States

  • University of Illinois at Chicago- Site Number : 8400003

    RECRUITING

    Chicago, Illinois, 60607, United States

  • University of Miami Don Suffer Clinical Research Building- Site Number : 8400036

    RECRUITING

    Miami, Florida, 33136, United States

  • Velocity Clinical Research - Lafayette- Site Number : 8400026

    RECRUITING

    Lafayette, Louisiana, 70508, United States

  • Velocity Clinical Research - San Diego- Site Number : 8400041

    RECRUITING

    La Mesa, California, 91942, United States

Conditions

Explore the condition pages connected to this study.