New drug ITC-6146RO enters first human tests for tough cancers

NCT ID NCT07423117

Not yet recruiting Disease control Sponsor: IntoCell, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests an experimental drug called ITC-6146RO in about 102 adults with advanced or metastatic cancers (like prostate, lung, or breast cancer) that have not improved with standard treatments. The study has two parts: first, finding a safe dose, then checking how well the drug works and its side effects. The main goal is safety, not yet a cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ITC-6146RO (an experimental drug given by IV infusion)
What this could lead to: If this works, it could point toward a new treatment option for people with advanced cancers that have not responded to standard therapies.
What could go wrong: This is a very early (Phase 1) trial with only 102 participants, so the drug may not work or could have serious side effects. It is too soon to know if it will help patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic malignant neoplasm metastatic prostate carcinoma Neoplasm Metastasis non-small cell lung carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC CASTRATION-RESISTANT PROSTATE CANCER METASTATIC SOLID TUMOR NON-SMALL CELL LUNG CANCER TRIPLE NEGATIVE BREAST CANCER

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