New drug aims to tame hidden hormone problem linked to weight and diabetes

NCT ID NCT07247058

Recruiting now Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated Apr 25, 2026 · Updated 16 times

Summary

This study tests whether the drug Isturisa can improve health problems caused by mild autonomous cortisol secretion (MACS), a condition where the body makes too much cortisol. Ten adults with MACS will take Isturisa for two years while researchers track changes in blood sugar, cholesterol, weight, bone density, and quality of life. The goal is to see if the drug can help control these issues better than current care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Johns Hopkins University School of Medicine
RECRUITING

Baltimore, Maryland, 21205, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

MILD AUTONOMOUS CORTISOL SECRETION (MACS)