New drug targets hidden hormone problem that affects metabolism

NCT ID NCT07247058

Recruiting now Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 13, 2026 · Updated 17 times

Summary

This study tests whether the drug Isturisa can improve health in people with mild autonomous cortisol secretion (MACS), a condition where the body makes too much cortisol. Researchers will measure changes in blood sugar, cholesterol, weight, bone density, and quality of life over two years. Ten adults with MACS and an adrenal adenoma will take Isturisa and be closely monitored.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Johns Hopkins University School of Medicine
RECRUITING

Baltimore, Maryland, 21205, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

MILD AUTONOMOUS CORTISOL SECRETION (MACS)