Could a simple gas help COPD patients avoid breathing tubes?

NCT ID NCT07191470

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a mild gas medicine called isoflurane, given through a special device (AnaConDa), helps people with severe COPD flare-ups feel more comfortable during non-invasive ventilation (a breathing mask). Ten adults with COPD and high carbon dioxide levels took part. The goal was to see if the gas could reduce agitation and the need for a breathing tube. Researchers monitored vital signs and comfort levels over 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
isoflurane gas
What this could lead to
If it works, this could offer a way to make breathing support more comfortable for COPD patients during severe flare-ups, potentially reducing the need for a breathing tube.
What could go wrong
This is a very small, early study with only 10 participants, so results may not apply to everyone. Risks include too much sedation, low blood pressure, or slowed breathing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences

    Rohtak, Haryana, 124001, India

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