Could a simple gas help COPD patients avoid breathing tubes?
NCT ID NCT07191470
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether a mild gas medicine called isoflurane, given through a special device (AnaConDa), helps people with severe COPD flare-ups feel more comfortable during non-invasive ventilation (a breathing mask). Ten adults with COPD and high carbon dioxide levels took part. The goal was to see if the gas could reduce agitation and the need for a breathing tube. Researchers monitored vital signs and comfort levels over 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
isoflurane gas
What this could lead to
If it works, this could offer a way to make breathing support more comfortable for COPD patients during severe flare-ups, potentially reducing the need for a breathing tube.
What could go wrong
This is a very small, early study with only 10 participants, so results may not apply to everyone. Risks include too much sedation, low blood pressure, or slowed breathing.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences
Rohtak, Haryana, 124001, India