Tiny study probes why islet transplants protect against low blood sugar

NCT ID NCT03079921

First seen May 12, 2026 · Last updated May 13, 2026 · Updated 1 time

Summary

This early-phase study looked at how nerve signals and the hormone epinephrine influence blood sugar regulation in 9 people with type 1 diabetes who had received islet cell transplants. Researchers used medications to block specific nerve and hormone pathways during controlled low blood sugar events. The goal was to understand why these transplants help prevent dangerous low blood sugar, not to test a new treatment.

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Contacts and locations

Locations

  • University of Pennsylvania - Institute for Diabetes, Obesity and Metabolism

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.