New islet transplant trial aims to free type 1 diabetes patients from severe low blood sugar

NCT ID NCT00679042

First seen Apr 07, 2026 · Last updated May 05, 2026 · Updated 2 times

Summary

This phase 3 trial tests whether transplanting insulin-producing cells (islets) from donors can improve blood sugar control in 21 adults with type 1 diabetes who still experience dangerous low blood sugar episodes despite intensive insulin therapy. Participants receive the islet infusion along with lifelong immune-suppressing drugs to prevent rejection. The main goal is to see if patients can achieve a safe blood sugar level (HbA1c ≤ 6.5%) without severe hypoglycemia one year after transplant.

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Contacts and locations

Locations

  • University of Illinois at Chicago Medical Center

    Chicago, Illinois, 60612, United States

Conditions

Explore the condition pages connected to this study.