Electric pulses zap thyroid cancer in neck without surgery

NCT ID NCT07328243

Recruiting now Disease control Sponsor: Tian'an Jiang Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This trial is testing a device that uses electrical pulses to destroy cancer cells in neck lymph nodes of people with thyroid cancer that has come back after surgery. About 85 participants will receive one or two treatments under ultrasound guidance. The main goal is to see how much the treated lymph nodes shrink after 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Irreversible Electroporation (IRE) Ablation device
What this could lead to: If successful, this could offer a non-surgical option to control recurrent thyroid cancer in the neck, potentially reducing the need for repeat surgeries.
What could go wrong: This is an early exploratory trial with only 85 participants and no comparison group. The procedure may not fully eliminate cancer cells, and risks include pain, nerve damage, or incomplete ablation.

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Conditions

The condition(s) this trial relates to.

Lymphatic Metastasis metastatic malignant neoplasm in the lymph nodes thyroid cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPH NODE METASTASIS THYROID CANCER PATIENTS

Contacts and locations

Locations

The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310000, China
The Third Affiliated Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310022, China

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