Personalized breathing machine settings fail to prove benefit in small ARDS trial

NCT ID NCT04012073

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 29 times

Summary

This study tested a new way to set breathing machines for people with severe lung injury (ARDS). Doctors used a special measurement to adjust the machine's pressure for each patient. The trial was stopped early after enrolling only 18 participants, so it could not show if this approach helped patients survive or recover faster.

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Contacts and locations

Locations

  • Azienda ospedaliera universitaria di Ferrara-arcispedale Sant'Anna

    Ferrara, Italy

  • Azienda ospedaliero-universitaria Mater Domini

    Catanzaro, Italy

  • Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico

    Milan, Italy

  • Fondazione IRCCS Policlinico San Matteo

    Pavia, Italy

  • Fondazione Policlinico Universitaro A. Gemelli IRCCS

    Rome, Italy

  • Ospedale San Gerardo

    Monza, Italy

  • Ospedale San Martino

    Genova, Italy

  • Policlinico Sant'Orsola

    Bologna, Italy

  • Policlinico di Bari

    Bari, Italy

  • SS. Annunziata hospital

    Chieti, Italy

Conditions

Explore the condition pages connected to this study.