New drug cocktail IoVeX aims to tame relapsed leukemia

NCT ID NCT06863259

First seen Feb 20, 2026 · Last updated Apr 30, 2026 · Updated 10 times

Summary

This early-phase trial tests whether a combination of three drugs (inotuzumab ozogamicin, venetoclax, and dexamethasone) is safe for people whose B-cell acute lymphoblastic leukemia has returned. About 28 children and adults will receive the treatment over one or two 28-day cycles. The main goal is to identify side effects and see if the drugs are tolerable.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.