First test of new drug for rare brain disease begins

NCT ID NCT04165486

Recruiting now Disease control Sponsor: Ionis Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This is the first study in people to test the safety and side effects of an experimental drug called ION464 for multiple system atrophy (MSA), a rare and serious brain disorder. About 40 adults with MSA will receive the drug or a placebo via a spinal injection to see how their bodies handle it. The main goal is to understand if the treatment is safe and to measure how much of the drug gets into the body and brain over time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CHU de Lyon - Hospices Civils de Lyon-H6pital Pierre Wertheimer, Neurologique HCL
RECRUITING

Lyon, 69500, France
Groupe Hospitalier Pitie-Salpetriere
RECRUITING

Paris, 75013, France
Hopital Purpan
RECRUITING

Toulouse, 31059, France
Hospital Beatriz Ângelo
RECRUITING

Loures, 2674-514, Portugal
Institute of Neurology & The National Hospital for Neurology and Neurosurgery
RECRUITING

London, England, WC1N 3BG, United Kingdom
Klinikum der Universtiatet Muenchen -Campus Grosshadern
RECRUITING

München, 81377, Germany
Medizinische Hochschule Hannover (MHH)
RECRUITING

Hanover, 30625, Germany
Medizinische Universität Innsbruck
RECRUITING

Innsbruck, 6020, Austria
Salford Royal Hospital
RECRUITING

Salford, M6 8HD, United Kingdom
Southampton General Hospital
RECRUITING

Southampton, SO16 6YD, United Kingdom
The John Radcliffe Hospital
RECRUITING

Oxford, England, OX3 9DU, United Kingdom
Universitaetsklinikum Duesseldorf AoeR
RECRUITING

Düsseldorf, 40225, Germany
Universitaetsklinikum Ulm
RECRUITING

Ulm, Baden-Wurttemberg, 89081, Germany
University Hospital Marburg
RECRUITING

Marburg, 35043, Germany

Conditions

Explore the condition pages connected to this study.

MULTIPLE SYSTEM ATROPHY