New drug combo targets tough pancreatic cancer in early trial

NCT ID NCT05586516

First seen Apr 09, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This early-phase trial tested a new oral drug called IOA-289, alone and with standard chemotherapy, in 16 adults with metastatic pancreatic cancer that cannot be removed by surgery. The main goal was to check safety and find the right dose. Researchers also looked at how the drug moves through the body and any signs of tumor shrinkage.

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Contacts and locations

Locations

  • Beatson West of Scotland Cancer Center

    Glasgow, G12 0YN, United Kingdom

  • Medical Oncology and Immunotherapy Unit, University Hospital of Siena

    Siena, 53100, Italy

  • UO Oncologia of Azienda Ospedaliera Universitaria Integrata di Verona

    Verona, Verona, 37126, Italy

Conditions

Explore the condition pages connected to this study.