Nasal spray may stop Epidural-Related fever in childbirth
NCT ID NCT07501221
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests whether a single dose of dexmedetomidine nasal spray, given before an epidural, can prevent fever during labor. 446 women having vaginal deliveries will be randomly assigned to receive either the drug or a placebo. The goal is to see if this simple approach reduces the risk of fever, which can cause complications for both mother and baby.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Dexmedetomidine nasal spray
- What this could lead to
- If it works, this could offer a simple, non-invasive way to prevent fever during labor, improving safety for mothers and babies.
- What could go wrong
- This is an early-stage trial with a moderate number of participants. The effect may be small or not work at all, and there are risks like low heart rate or low blood pressure.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chengdu Jinjiang District Women & Children Health Hospital
Chengdu, Sichuan, 610011, China
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