Aggressive cholesterol therapy may halt artery clogging in younger heart patients

NCT ID NCT06896708

First seen Jan 05, 2026 · Last updated May 15, 2026 · Updated 23 times

Summary

This study tests whether intensive cholesterol-lowering (LDL-C below 1.0 mmol/L) can slow the buildup of artery plaque better than standard treatment (LDL-C below 1.8 mmol/L) in adults aged 18-60 with chronic coronary syndrome. About 766 participants will be randomly assigned to one of two treatment goals and followed for at least 2 years. The main goal is to see if intensive therapy reduces plaque progression, heart attacks, death, or hospitalizations.

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Contacts and locations

Locations

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, Guangdong, 510100, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Eighth Affiliated Hospital of Sun Yat-sen University

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, 518033, China

  • The First Affiliated Hospital of Chongqing Medical University

    NOT_YET_RECRUITING

    Chongqing, Chongqing Municipality, 400015, China

  • The First Affiliated Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116000, China

  • The Ninth Clinical Medical College of Guangzhou University of Chinese Medicine

    NOT_YET_RECRUITING

    Dongguan, Guangdong, 523000, China

  • The Third Affiliated Hospital of Guangzhou Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510000, China

  • Zhongshan People's Hospital

    NOT_YET_RECRUITING

    Zhongshan, Guangdong, 528400, China

Conditions

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