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5-Day brain zapping shows promise for stubborn depression

NCT ID NCT06166082

Completed Symptom relief Sponsor: Changping Laboratory Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an intensive form of brain stimulation for people with depression that hasn't responded to other treatments. 130 participants received either real or fake stimulation over 5 days, with 10 sessions per day. The goal was to see if this approach could quickly reduce depression symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
intensive accelerated intermittent theta burst stimulation (a form of brain stimulation using magnetic pulses)
What this could lead to
If it works, this could offer a fast-acting, non-drug option for people with depression that hasn't improved with standard treatments.
What could go wrong
This is a completed trial, but it's still early-stage research. The results may not apply to everyone, and the intensive schedule may be hard to tolerate for some.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TREATMENT RESISTANT DEPRESSION

Contacts and locations

Locations

  • Hebei Mental Health Center

    Baoding, China

  • HuiLongGuan Hospital

    Beijing, China

  • Wuhan Mental Health Center

    Wuhan, China

  • Xianyue Hospital

    Xiamen, China

  • Zhumadian Second People's Hospital

    Zhumadian, China

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