New trial aims to stop bipolar depression before it worsens

NCT ID NCT05973786

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 30 times

Summary

This study tests whether starting a stronger, six-week treatment plan early can help people with bipolar depression who did not get better with their first medication. About 418 adults will either receive the intensified treatment or continue with standard care. The goal is to see if early action leads to better symptom control and remission.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliero-Universitaria "Città della Salute e della Scienza di Torino"

    RECRUITING

    Turin, Italy

    Contact Email: •••••@•••••

  • Eginition hospital, department of psychiatry

    NOT_YET_RECRUITING

    Athens, 11528, Greece

    Contact Email: •••••@•••••

  • Fundació Clínic per a la Recerca Biomèdica

    RECRUITING

    Barcelona, Spain

    Contact Email: •••••@•••••

  • King's College London, Psychiatry & Cognitive Neuroscience

    NOT_YET_RECRUITING

    London, SE5 8AF, United Kingdom

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Klinik für Psychiatrie und Psychotherapie der Universitätsmedizin Mainz

    RECRUITING

    Mainz, Germany

    Contact Email: •••••@•••••

  • LWL-Klinik Dortmund, Bereich Forschung & Wissenschaft

    RECRUITING

    Dortmund, 44287, Germany

    Contact Email: •••••@•••••

  • Medical University Innsbruck

    RECRUITING

    Innsbruck, Austria

    Contact Email: •••••@•••••

  • Universita degli Studi di Brescia

    RECRUITING

    Brescia, Italy

    Contact Email: •••••@•••••

  • University Hospital Frankfurt am Main - Goethe University

    RECRUITING

    Frankfurt am Main, Germany

    Contact Email: •••••@•••••

  • University of Cagliari

    RECRUITING

    Cagliari, Italy

    Contact Email: •••••@•••••

  • Università degli studi della Campania Luigi Vanvitelli

    RECRUITING

    Naples, 80138, Italy

    Contact Email: •••••@•••••

  • Universitätsklinik für Psychiatrie und Psychotherapie Bielefeld

    RECRUITING

    Bielefeld, Germany

    Contact Email: •••••@•••••

  • Westfälische Wilhelms-Universität Münster

    RECRUITING

    Münster, Germany

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.