Experimental drug aims to halt rare heart disease

NCT ID NCT03702829

First seen Feb 20, 2026 · Last updated May 15, 2026 · Updated 12 times

Summary

This study tested a drug called inotersen in 31 adults with TTR amyloid cardiomyopathy, a condition where abnormal protein builds up in the heart and causes progressive damage. The drug works by reducing the production of that protein in the liver. The goal was to see if it could slow or stop heart decline over 24 months, but the study was ended early.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AMYLOIDOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.