Breathe in protection: inhaled COVID vaccine trial launches

NCT ID NCT06381739

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new COVID-19 vaccine that you breathe in as a mist, instead of getting a shot. It aims to see if it is safe and creates a strong immune response in the lungs and blood. About 350 healthy adults who have already had three mRNA COVID vaccines will receive either the experimental vaccine or a placebo. Researchers will monitor them for 24 weeks to track side effects and immune reactions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ChAd-triCoV/Mac (a viral-vector vaccine)

What this could lead to

If successful, this could lead to a needle-free COVID-19 vaccine that boosts lung immunity and may offer better protection against infection.

What could go wrong

This is a phase 2 trial with only 350 participants, so results may not apply to everyone. The vaccine is still experimental, and side effects or limited effectiveness are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Canadian Center for Vaccinology, Dalhousie University

    RECRUITING

    Halifax, Nova Scotia, B3K 6R8, Canada

    Contact

    Contact Phone: •••-•••-••••

  • Health Sciences Centre

    RECRUITING

    Hamilton, Ontario, L8S 4K1, Canada