New drug combo aims to tame tough autoimmune diseases

NCT ID NCT06570798

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests two medications, inebilizumab and blinatumomab, in adults with active lupus (with kidney inflammation) or hard-to-treat rheumatoid arthritis. The goal is to see if these drugs are safe and can help control the diseases. About 220 people will take part. This is not a cure; participants may still need ongoing treatment.

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Conditions

The condition(s) this trial relates to.

lupus nephritis rheumatoid arthritis systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTIVE REFRACTORY RHEUMATOID ARTHRITIS SYSTEMIC LUPUS ERYTHEMATOSUS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Addenbrookes Hospital
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Al Kuwait Hospital Dubai ehs
RECRUITING

Dubai, 22241, United Arab Emirates
Bioresearch Partner Coral Terrace
RECRUITING

South Miami, Florida, 33143, United States
Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez
RECRUITING

Lille, 59037, France
Centre Hospitalier Universitaire de Liege - Sart Tilman
RECRUITING

Liège, 4000, Belgium
Centre Hospitalier Universitaire de Lyon - Hopital Edouard Herriot
RECRUITING

Lyon Cédex 3, 69437, France
Centre Hospitalier Universitaire de Lyon- Hopital Edouard Herriot
RECRUITING

Lyon, 69437, France
Centre Hospitalier Universitaire de Strasbourg - Hopital de Hautepierre
RECRUITING

Strasbourg, 67098, France
Centre Hospitalier Universitaire de Strasbourg - Nouvel Hopital Civil
RECRUITING

Strasbourg, 67091, France
Centre Hospitalier Universitaire de Toulouse - Hopital Purpan
RECRUITING

Toulouse, 31059, France
Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil
RECRUITING

Toulouse, 31059, France
Cleveland Clinic Abu Dhabi
RECRUITING

Abu Dhabi, United Arab Emirates
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Cliniques Universtaire Saint Luc Universite Catholique de Louvain
RECRUITING

Brussels, 1200, Belgium
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Homestead Associates In Research Inc
TERMINATED

Homestead, Florida, 33033, United States
HonorHealth Research and Innovation Institute
RECRUITING

Scottsdale, Arizona, 85258, United States
Hopital Bichat Claude Bernard
RECRUITING

Paris, 75018, France
Hopital Cochin
RECRUITING

Paris, 75014, France
Hopital Europeen Georges Pompidou
RECRUITING

Paris, 75908, France
Hopital de la Conception
RECRUITING

Marseille, 13005, France
Hospital Clinic i Provincial de Barcelona
RECRUITING

Barcelona, Catalonia, 08036, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre
COMPLETED

Madrid, 28041, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Marques de Valdecilla
TERMINATED

Santander, Cantabria, 39008, Spain
Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre
RECRUITING

Le Kremlin-Bicêtre, 94270, France
IRCCS Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy
IRCCS Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
Klinikum der LMU Muenchen
RECRUITING

München, 80336, Germany
Krankenhaus Porz am Rhein gGmbH
RECRUITING

Cologne, 51149, Germany
Leicester General Hospital
RECRUITING

Leicester, LE5 4PW, United Kingdom
Linear Clinical Research Limited
RECRUITING

Perth, Western Australia, 6009, Australia
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
MetroHealth Medical Center
RECRUITING

Cleveland, Ohio, 44109, United States
Northwell Health
RECRUITING

Great Neck, New York, 11021, United States
Ospedale San Giovanni Bosco
RECRUITING

Turin, 10154, Italy
Prolato Clinical Research Center
COMPLETED

Houston, Texas, 77054, United States
Royal Victoria Infirmary
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
Seattle Rheumatology Associates
RECRUITING

Seattle, Washington, 98104, United States
Sheikh Shakhbout Medical City
RECRUITING

Abu Dhabi, 11001, United Arab Emirates
Unidade Local de Saude de Gaia-Espinho, EPE
RECRUITING

Vila Nova de Gaia, 4430-502, Portugal
Unidade Local de Saude de Lisboa Ocidental, EPE - Hospital Santa Cruz
RECRUITING

Carnaxide, 2790-134, Portugal
Unidade Local de Saude de Sao Jose, EPE - Hospital Curry Cabral
RECRUITING

Vila Franca de Xira, 2600-076, Portugal
Universitaetsklinikum Duesseldorf AoeR
RECRUITING

Düsseldorf, 40225, Germany
Universitaetsklinikum Leipzig
RECRUITING

Leipzig, 04103, Germany
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
RECRUITING

Leuven, 3000, Belgium
University Medical Center New Orleans
RECRUITING

New Orleans, Louisiana, 70112, United States
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of Rochester Medical Center
RECRUITING

Rochester, New York, 14642, United States
Vida Research Center
TERMINATED

Hialeah, Florida, 33010, United States
Vitaly Clinical Research
TERMINATED

Miami, Florida, 33125, United States
Westchester Medical Center
COMPLETED

Hawthorne, New York, 10532, United States
Western General hospital
RECRUITING

Edinburgh, EH4 2XU, United Kingdom

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