New combo therapy shows promise against tough pancreatic cancer

NCT ID NCT02077881

First seen Apr 10, 2026 · Last updated May 13, 2026 · Updated 6 times

Summary

This study tested adding an experimental immune-boosting drug called indoximod to standard chemotherapy for people with pancreatic cancer that has spread to other parts of the body. The goal was to find the safest dose and see if the combination helps patients live longer. A total of 157 adults with metastatic pancreatic cancer took part.

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Contacts and locations

Locations

  • Augusta University

    Augusta, Georgia, 30912, United States

  • Gibbs Cancer Center and Research Institute

    Spartanburg, South Carolina, 29303, United States

  • Greenville Health Systems

    Greenville, South Carolina, 29605, United States

  • Huntsman Cancer Center

    Salt Lake City, Utah, 84112, United States

  • Stanford University

    Palo Alto, California, 94304, United States

  • The Vally Hospital

    Paramus, New Jersey, 07652, United States

  • The West Clinic

    Memphis, Tennessee, 38120, United States

  • University of Kentucy

    Lexington, Kentucky, 40536, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.