New shot challenges pill in battle against high cholesterol

NCT ID NCT06431763

First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study tested two drugs—inclisiran (a shot) and bempedoic acid (a pill)—in 402 adults with high cholesterol and heart disease who were already on statins. The goal was to see which one lowers LDL (bad) cholesterol more. Results will help doctors choose the best treatment to control cholesterol and reduce heart risks.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Berlin, 13347, Germany

  • Novartis Investigative Site

    Berlin, 13353, Germany

  • Novartis Investigative Site

    Bochum, 44789, Germany

  • Novartis Investigative Site

    Bochum, 44791, Germany

  • Novartis Investigative Site

    Bremen, 28277, Germany

  • Novartis Investigative Site

    Dessau, 06846, Germany

  • Novartis Investigative Site

    Dresden, 01307, Germany

  • Novartis Investigative Site

    Erfurt, 99097, Germany

  • Novartis Investigative Site

    Essen, 45147, Germany

  • Novartis Investigative Site

    Essen, 45355, Germany

  • Novartis Investigative Site

    Falkensee, 14612, Germany

  • Novartis Investigative Site

    Gladbeck, 45968, Germany

  • Novartis Investigative Site

    Hamburg, 21109, Germany

  • Novartis Investigative Site

    Hamburg, 22041, Germany

  • Novartis Investigative Site

    Hamburg, 22607, Germany

  • Novartis Investigative Site

    Hoyerswerda, 02977, Germany

  • Novartis Investigative Site

    Kassel, 34121, Germany

  • Novartis Investigative Site

    Kiel, 24105, Germany

  • Novartis Investigative Site

    Ludwigshafen, 67067, Germany

  • Novartis Investigative Site

    Magdeburg, 39120, Germany

  • Novartis Investigative Site

    Markkleeberg, 04416, Germany

  • Novartis Investigative Site

    Meissen, 01662, Germany

  • Novartis Investigative Site

    Münster, 48149, Germany

  • Novartis Investigative Site

    Offenbach, 63065, Germany

  • Novartis Investigative Site

    Papenburg, 26871, Germany

  • Novartis Investigative Site

    Pirna, 01796, Germany

  • Novartis Investigative Site

    Potsdam, 14471, Germany

  • Novartis Investigative Site

    Rüdersdorf, 15562, Germany

  • Novartis Investigative Site

    Saint Ingbert Oberw, 66386, Germany

  • Novartis Investigative Site

    Ulm, 89077, Germany

  • Novartis Investigative Site

    Völklingen, 66333, Germany

  • Novartis Investigative Site

    Mannheim, Baden-Wurttemberg, 68305, Germany

  • Novartis Investigative Site

    Stuttgart, Baden-Wurttemberg, 70376, Germany

  • Novartis Investigative Site

    Lichtenfels, Bavaria, 96215, Germany

  • Novartis Investigative Site

    Muehldorf Am Inn, Bavaria, 84453, Germany

  • Novartis Investigative Site

    Regensburg, Bavaria, 93053, Germany

  • Novartis Investigative Site

    Sulzbach-Rosenberg, Bavaria, 92237, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60389, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60590, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60594, Germany

  • Novartis Investigative Site

    Göttingen, Lower Saxony, 37075, Germany

  • Novartis Investigative Site

    Essen, North Rhine-Westphalia, 45355, Germany

  • Novartis Investigative Site

    Koeln Nippes, North Rhine-Westphalia, 50733, Germany

  • Novartis Investigative Site

    Löhne, North Rhine-Westphalia, 32584, Germany

  • Novartis Investigative Site

    Kaiserslautern, Rhineland-Palatinate, 67655, Germany

  • Novartis Investigative Site

    Dresden, Saxony, 01099, Germany

  • Novartis Investigative Site

    Dresden, Saxony, 01307, Germany

  • Novartis Investigative Site

    Leipzig, Saxony, 04209, Germany

  • Novartis Investigative Site

    Jena, Thuringia, 07740, Germany

  • Novartis Investigative Site

    Aachen, 52074, Germany

  • Novartis Investigative Site

    Bad Homburg, 61348, Germany

  • Novartis Investigative Site

    Bad Krozingen, 79189, Germany

  • Novartis Investigative Site

    Bad Oeynhausen, 32545, Germany

  • Novartis Investigative Site

    Bamberg, 96049, Germany

  • Novartis Investigative Site

    Berlin, 10367, Germany

Conditions

Explore the condition pages connected to this study.