New drug inclisiran aims to lower cholesterol better in chinese heart patients

NCT ID NCT06941792

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether inclisiran, a newer cholesterol-lowering drug, works better than standard treatments for Chinese patients with coronary heart disease. About 1,590 adults whose cholesterol is still high despite statins will receive either inclisiran or usual care. The main goal is to see how much LDL cholesterol drops after one year and how many patients reach their target levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

inclisiran

What this could lead to

If it works, this could offer a more effective way to control cholesterol and reduce heart disease risk in Chinese patients.

What could go wrong

This is a phase 4 trial, so inclisiran is already approved; the main question is how it performs in real-world Chinese patients. It may not show a big advantage over standard care, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Novartis Investigated Site

    Taiyuan, Shanxi, 030000, China

  • Novartis Investigative Site

    Anqing, Anhui, 246003, China

  • Novartis Investigative Site

    Beijing, Beijing Municipality, 102218, China

  • Novartis Investigative Site

    Chongqing, Chongqing Municipality, 400010, China

  • Novartis Investigative Site

    Longyan, Fujian, 364099, China

  • Novartis Investigative Site

    Jiamusi, Heilongjiang, 154002, China

  • Novartis Investigative Site

    Zhengzhou, Henan, 451400, China

  • Novartis Investigative Site

    Baotou, Inner Mongolia, 014010, China

  • Novartis Investigative Site

    Shenyang, Liaoning, 110016, China

  • Novartis Investigative Site

    Shenyang, Liaoning, 121100, China

  • Novartis Investigative Site

    Jining, Shandong, 272000, China

  • Novartis Investigative Site

    Weifang, Shandong, 261000, China

  • Novartis Investigative Site

    Shanghai, Shanghai Municipality, 200065, China

  • Novartis Investigative Site

    Chengdu, Sichuan, 610031, China

  • Novartis Investigative Site

    Ürümqi, Xinjiang Uygur Autonomous Region, 830054, China

  • Novartis Investigative Site

    Hangzhou, Zhejiang, 310007, China

  • Novartis Investigative Site

    Jinhua, Zhejiang, 321000, China

  • Novartis Investigative Site

    Ningbo, Zhejiang, 315000, China

  • Novartis Investigative Site

    Wenzhou, Zhejiang, 325000, China