New drug combo targets Hard-to-Treat cancers

NCT ID NCT06873789

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests an experimental drug called INCB177054, given alone or with another drug (retifanlimab), in people with advanced or metastatic solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. About 9 participants are expected to take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal squamous cell carcinoma head and neck squamous cell carcinoma metastatic malignant neoplasm neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer and Hematology Centers of Western Michigan-Start Midwest

    Grand Rapids, Michigan, 49546, United States

  • Carolina Bio Oncology

    Huntersville, North Carolina, 28078, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Providence Cancer Institute Franz Clinic

    Portland, Oregon, 97213, United States

  • South Texas Accelerated Research Therapeutics

    San Antonio, Texas, 78229, United States

  • The Angeles Clinic and Research Institute

    Los Angeles, California, 90025, United States

  • University of Florida Health Shands Hospital

    Gainesville, Florida, 32610, United States

  • Upmc Cancercenter

    Pittsburgh, Pennsylvania, 15232, United States

  • Valkyrie Clinical Trials

    Panorama City, California, 91402, United States