New drug combo targets Hard-to-Treat cancers

NCT ID NCT06873789

Ongoing Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests an experimental drug called INCB177054, given alone or with another drug (retifanlimab), in people with advanced or metastatic solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. About 9 participants are expected to take part.

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Conditions

The condition(s) this trial relates to.

anal squamous cell carcinoma head and neck squamous cell carcinoma metastatic malignant neoplasm neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMORS METASTATIC SOLID TUMORS SOLID TUMORS

Contacts and locations

Locations

Cancer and Hematology Centers of Western Michigan-Start Midwest

Grand Rapids, Michigan, 49546, United States
Carolina Bio Oncology

Huntersville, North Carolina, 28078, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Providence Cancer Institute Franz Clinic

Portland, Oregon, 97213, United States
South Texas Accelerated Research Therapeutics

San Antonio, Texas, 78229, United States
The Angeles Clinic and Research Institute

Los Angeles, California, 90025, United States
University of Florida Health Shands Hospital

Gainesville, Florida, 32610, United States
Upmc Cancercenter

Pittsburgh, Pennsylvania, 15232, United States
Valkyrie Clinical Trials

Panorama City, California, 91402, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.