Early cancer drug trial halted after initial safety testing

NCT ID NCT04272034

Summary

This early-stage study tested a new drug called INCB099318 in people with advanced solid tumors that had stopped responding to standard treatments. The main goal was to check the drug's safety, how the body processes it, and what side effects it might cause. The trial was terminated early, and it involved 105 participants with various advanced cancers who had no other good treatment options.

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Contacts and locations

Locations

  • Docrates Cancer Center

    Helsinki, 00180, Finland

  • Freeman Hospital Newcastle Upon Tyne Foundation Nhs Trust

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Ghent University Hospital

    Ghent, 09000, Belgium

  • Guys and St Thomas Nhs Foundation Trust

    London, SE1 9RT, United Kingdom

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Haukeland University Hospital

    Bergen, 05051, Norway

  • Helsinki University Central Hospital

    Helsinki, 00029, Finland

  • Imperial College Healthcare Nhs Trust - Hammersmith Hospital

    London, W12 0HS, United Kingdom

  • Institut Jules Bordet

    Brussels, B-1070, Belgium

  • Karolinska University Hospital Solna

    Solna, 17164, Sweden

  • Oslo University Hospital

    Oslo, 00450, Norway

  • Prisma Health Cancer Institute Faris

    Greenville, South Carolina, 29605, United States

  • Rigshospitalet Uni of Hospital of Copenhagen

    Copenhagen, 02100, Denmark

  • Sahlgrenska University Hospital

    Gothenburg, 41345, Sweden

  • St James University Hospital

    Leeds, LS9 7TF, United Kingdom

  • Tampere University Hospital

    Tampere, 33520, Finland

  • The Royal Marsden Hospital Nhs Trust London

    London, SM2 5PT, United Kingdom

  • Turku University Hospital

    Turku, 20520, Finland

  • Universitair Ziekenhuis Antwerpen (Uza)

    Edegem, 02650, Belgium

  • Universitair Ziekenhuis Brussel

    Brussels, 01090, Belgium

  • Universitaire Ziekenhuis Leuven - Gasthuisberg

    Leuven, 03000, Belgium

  • Uppsala Universitet - Akademiska Sjukhuset

    Uppsala, 75185, Sweden

  • Vanderbilt-Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

  • Western General Hospital

    Edinburgh, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.