New screening tool aims to catch hidden arthritis in psoriasis patients
NCT ID NCT06382051
First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 4 times
Summary
This Canadian study tests whether adding two questions about morning stiffness and lower back pain to a standard screening tool (PEST) can help dermatologists identify psoriatic arthritis earlier in people with moderate-to-severe plaque psoriasis. About 502 adults who are candidates for biologic medications will complete the screening, and those flagged will see a rheumatologist for confirmation. The goal is to improve early diagnosis and prevent joint damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PEST screening tool with two additional questions
- What this could lead to
- If successful, this could lead to a better screening tool that helps dermatologists identify psoriatic arthritis earlier in psoriasis patients.
- What could go wrong
- This is an observational study, not a treatment trial. The new screening questions may not significantly improve detection rates, and results may not apply outside Canada.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Novartis Investigative Site
RECRUITINGCalgary, Alberta, T2J 7E1, Canada
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Novartis Investigative Site
RECRUITINGEdmonton, Alberta, T5J 3S9, Canada
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Novartis Investigative Site
RECRUITINGEdmonton, Alberta, T6G 2C8, Canada
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Novartis Investigative Site
RECRUITINGKelowna, British Columbia, V1W 4V5, Canada
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Novartis Investigative Site
RECRUITINGSurrey, British Columbia, V3R 6A7, Canada
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Novartis Investigative Site
RECRUITINGWinnipeg, Manitoba, R3C 0N2, Canada
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Novartis Investigative Site
RECRUITINGFredericton, New Brunswick, E3B 1G9, Canada
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Novartis Investigative Site
RECRUITINGBarrie, Ontario, L4M 6L2, Canada
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Novartis Investigative Site
RECRUITINGGreater Sudbury, Ontario, P3C 1X8, Canada
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Novartis Investigative Site
RECRUITINGHamilton, Ontario, L8J 0G5, Canada
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Novartis Investigative Site
RECRUITINGHamilton, Ontario, L8N 1V6, Canada
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Novartis Investigative Site
RECRUITINGHamilton, Ontario, L8P4B4, Canada
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Novartis Investigative Site
RECRUITINGLondon, Ontario, N6A 5R9, Canada
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Novartis Investigative Site
RECRUITINGLondon, Ontario, N6G 0W7, Canada
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Novartis Investigative Site
RECRUITINGMarkham, Ontario, L3R 2C7, Canada
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Novartis Investigative Site
RECRUITINGOttawa, Ontario, K2A 3Z3, Canada
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Novartis Investigative Site
RECRUITINGRichmond Hill, Ontario, L4C 9M7, Canada
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Novartis Investigative Site
RECRUITINGStoney Creek, Ontario, L8G 1H1, Canada
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Novartis Investigative Site
RECRUITINGToronto, Ontario, M4A2S8, Canada
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Novartis Investigative Site
RECRUITINGToronto, Ontario, M5S 1B6, Canada
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Novartis Investigative Site
RECRUITINGWaterloo, Ontario, N2J 1C4, Canada
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Novartis Investigative Site
RECRUITINGMontreal, Quebec, H1T 2M4, Canada
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Novartis Investigative Site
RECRUITINGMontreal, Quebec, H1Y 3L1, Canada
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Novartis Investigative Site
RECRUITINGMontreal, Quebec, H4A 3T2, Canada
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Novartis Investigative Site
RECRUITINGQuébec, Quebec, G1V 4X7, Canada
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Novartis Investigative Site
RECRUITINGQuébec, Quebec, G1W 4R4, Canada
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Novartis Investigative Site
RECRUITINGSte-Foy, Quebec, G1V 4G2, Canada
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Novartis Investigative Site
RECRUITINGVerdun, Quebec, H4G 3E7, Canada
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Novartis Investigative Site
RECRUITINGSaskatoon, Saskatchewan, S7K 2C1, Canada
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Novartis Investigative Site
RECRUITINGSaskatoon, Saskatchewan, S7K0H6, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new injection clear psoriasis when other biologics fail?
- Can a gel tame psoriasis? new antibody fragment put to the test
- Can a Once-Daily cream tame psoriasis in toddlers?
- Can a new injection calm psoriatic arthritis?
- Can a new drug called ZP9830 calm psoriasis Flare-Ups?
- Can we predict psoriasis relapse after biologics? a new study digs into the clues.