New study tests if popping the last membrane gets labour going faster

NCT ID NCT07301957

First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 3 times

Summary

About 1 in 4 women have their water break before labour starts. Most go into labour within 48 hours, but some need to be induced. This study tests whether deliberately breaking the leftover membrane when a woman is admitted to the hospital can shorten the time to labour and reduce the need for induction. The trial will include 130 women with a single baby in head-down position.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
additional rupture of the residual membrane using a sterile amniotic membrane piercer (Robé device)
What this could lead to
If it works, this could reduce the time women wait for labour to start and lower the need for induced labour after their water breaks.
What could go wrong
This is a small, early-stage study with only 130 participants. It may not show a clear benefit, and the procedure carries a small risk of infection or discomfort.

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Conditions

The condition(s) this trial relates to.

Fetal Membranes, Premature Rupture preterm premature rupture of the membranes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Angers

    RECRUITING

    Angers, 49000, France

  • Centre Hospitalier Le Mans

    RECRUITING

    Le Mans, 72000, France

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