New combo therapy could let some avoid colorectal surgery

NCT ID NCT07403877

First seen Feb 12, 2026 · Last updated May 21, 2026 · Updated 16 times

Summary

This study tests three treatment plans for people with a specific type of colorectal cancer (MSI-H/dMMR) that has spread locally. The treatments use immunotherapy drugs (nivolumab and ipilimumab) with or without radiation before surgery. The goal is to shrink or eliminate the tumor, possibly allowing some patients to avoid surgery entirely. About 114 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

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