New Pre-Surgery treatment aims to shrink tumors and boost survival

NCT ID NCT04795661

Summary

This study is testing whether giving an immunotherapy drug called pembrolizumab before surgery can help people with certain localized, operable cancers. The goal is to see if this pre-surgery treatment can shrink or even eliminate the tumor, potentially leading to better long-term results. The trial will enroll 240 adults with specific types of cancer that have a particular genetic signature (MSI/dMMR), including colorectal and gastric cancers.

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Contacts and locations

Locations

  • APHP - Hôpital Saint-Antoine

    Paris, 75571, France

  • APHP Hôpital Saint-Louis

    Paris, 75010, France

  • CHU Amiens Picardie

    Amiens, 80054, France

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Saint Etienne

    Saint-Etienne, 42270, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre Georges-Francois Leclerc

    Dijon, 21079, France

  • Centre Léon Bérard

    Lyon, 69008, France

  • Centre Paul Strauss

    Strasbourg, 67200, France

  • Groupe Hospitalier Diaconesses Croix Saint-Simon

    Paris, 75571, France

  • Hopital Huriez

    Lille, 59037, France

  • Hôpital Européen Georges Pompidou

    Paris, 75015, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Institut de cancérologie Strasbourg Europe

    Strasbourg, 67200, France

  • Institut du Cancer Val d'Aurelle

    Montpellier, 34298, France

  • Institut mutualiste Montsouris

    Paris, 75014, France

Conditions

Explore the condition pages connected to this study.