New drug combo shows promise in taming advanced lung cancer

NCT ID NCT03581487

First seen Nov 06, 2025 · Last updated Jun 17, 2026 · Updated 27 times

Summary

This study tested a mix of two immunotherapy drugs (durvalumab and tremelimumab) plus a targeted therapy (selumetinib) in 40 people with stage IV non-small cell lung cancer that had returned. The goal was to find the safest dose and see if the combination could slow cancer growth. While not a cure, the approach aims to help the immune system fight the cancer and block tumor growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.