Hope for rare cancers: new immunotherapy combo tested in nationwide trial
NCT ID NCT06790706
First seen Nov 01, 2025 · Last updated Jun 08, 2026 · Updated 29 times
Summary
This study tests a combination of two immunotherapy drugs (domvanalimab and zimberelimab) in people with five types of rare advanced cancers that have not responded to standard treatment. The goal is to see if this treatment can shrink tumors or stop them from growing for at least 24 weeks. About 154 participants will receive the drugs and be monitored for side effects and disease progression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP-HM, TIMONE Hospital, medical oncology department
NOT_YET_RECRUITINGMarseille, 13009, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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AP-HP, Tenon Hospital, medical oncology department
NOT_YET_RECRUITINGParis, 75020, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Centre Eugène Marquis, medical oncology department
NOT_YET_RECRUITINGRennes, 35042, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Centre Hospitalier Universitaire de Lille, medical oncology department
NOT_YET_RECRUITINGLille, 59037, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospices Civils de Lyon, Medical Oncology Department, Edouard Herriot Hospital
RECRUITINGLyon, 69003, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospices Civils de Lyon, Medical Oncology Department, Lyon SUD Hospital
RECRUITINGPierre-Bénite, 69310, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospices Civils de Lyon, Thoracic Oncology Department, Louis Pradel Hospital
RECRUITINGBron, 69500, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Insitut de Cancérologie Strasbourg Europe, medical oncology department
NOT_YET_RECRUITINGStrasbourg, 67200, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institut Bergonié, medical oncology department
NOT_YET_RECRUITINGBordeaux, 33076, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institut Curie, thoracic oncology department
NOT_YET_RECRUITINGParis, 75005, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institut Gustave Roussy, medical oncology department
NOT_YET_RECRUITINGVillejuif, 94805, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institut Paoli-Calmettes Marseille, medical oncology department
NOT_YET_RECRUITINGMarseille, 13009, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institut Régional du Cancer de Montpellier, medical oncology department
NOT_YET_RECRUITINGMontpellier, 34298, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institut de Cancerologie de l'Ouest , medical oncology department
NOT_YET_RECRUITINGAngers, 49055, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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ONCOPOLE Claudius Regaud, IUCT-Oncopole, medical oncology department
NOT_YET_RECRUITINGToulouse, 31059, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
Explore the condition pages connected to this study.