Scientists launch major study to unravel mysteries of rare immune diseases

NCT ID NCT00001244

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 12 times

Summary

This study aims to understand the causes and progression of Common Variable Immunodeficiency (CVID) and related inborn errors of immunity. Researchers will observe up to 500 patients over time using blood tests, imaging, and other exams. The goal is to find better ways to diagnose, treat, and prevent complications, but no experimental treatment is given.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better ways to diagnose, treat, and prevent complications of CVID and related immune disorders.
What could go wrong
This is an observational study, not a treatment trial. It may not directly benefit participants, and results may take years to translate into new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.