Scientists hunt for hidden immune flaws in families with mystery infections

NCT ID NCT00001355

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study looks at people who get frequent or unusual infections, along with their family members, to find the genetic and biochemical causes of immune system problems. Researchers will collect blood, saliva, urine, and other samples to better understand these defects and develop better ways to diagnose and treat them. Up to 3,600 participants will be followed over time at the NIH.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.