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A new tooth in days? trial pits fast-loaded implants against the slow-and-steady approach

NCT ID NCT07882095

Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time

Summary

Researchers at Ain Shams University are comparing two ways to restore a missing front tooth with an implant placed straight into the fresh extraction socket. Eighty adults will be randomly assigned to receive a crown within 48 hours, using either a zirconia crown, a permanent 3D-printed resin crown, or a temporary printed resin crown, or to wait three months before a zirconia crown is attached. The study tracks changes in bone around the implant and measures how firmly each implant sits in the jaw. The goal is to see whether fast loading and different crown materials affect bone health and implant stability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dental implant loading protocols and crown materials, including immediate loading with zirconia or 3D-printed resin crowns versus conventional delayed loading
What this could lead to
If immediate loading holds up, people could get a finished-looking tooth within days of extraction instead of waiting months, and dentists would learn which crown material protects the bone best.
What could go wrong
Implants loaded right away can fail to fuse with the bone, especially in the front of the mouth where appearance matters. This is a single-center study of 80 people, so the results may not apply to every patient or clinic.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 21 years or older * Single tooth requiring extraction and replacement in the maxillary anterior or premolar region (sites 15 to 25), with a gap bounded by natural teeth * Adjacent tooth present * Opposing dentition of natural teeth or a fixed tooth- or implant-supported prosthesis * Extraction socket Elian Type I or Type II * Adequate oral hygiene: bleeding on probing \<20% and plaque index \<20% * Implant insertion torque ≥35 Ncm at placement Exclusion Criteria: * Pregnant or lactating women * Systemic or local contraindication to implant treatment * Smokers * Current drugs affecting bone metabolism * Bisphosphonate use in the last 4 years * Malignancy, radiotherapy or chemotherapy for malignancy in the past 5 years

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implant Partial edentulism Tooth loss in the esthetic zone requiring immediate implant placement

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ain Shams University

    Cairo, Cairo Governorate, 71111, Egypt

  • Assiut University

    Asyut, Asyut Governorate, 71111, Egypt

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