Breakthrough drug opens door to transplants for patients once considered untransplantable
NCT ID NCT07379957
Summary
This study is reviewing the results of using a drug called imlifidase for adult kidney transplant patients who are 'highly sensitized,' meaning their immune systems have developed many antibodies that make finding a compatible donor extremely difficult. The drug works by temporarily clearing these harmful antibodies, allowing a transplant from a deceased donor to proceed even if there was initially a positive crossmatch (a sign of incompatibility). Researchers will analyze data from 450 patients to see how well the transplants worked and how safe the treatment was over the long term.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Amiens Picardie Site Sud
Amiens, 80000, France
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CHU Caen Normandie
Caen, 14000, France
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CHU Saint Etienne
Saint-Etienne, 42000, France
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CHU Tours Bretonneau
Tours, 37000, France
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CHU de Grenoble Alpes
Grenoble, 38000, France
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CHU de Nantes
Nantes, 44000, France
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CHU de Reims
Reims, 51000, France
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CHU de Strasbourg
Strasbourg, 67000, France
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Hôpital Bicêtre
Paris, 75000, France
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Hôpital Edouard Herriot
Lyon, 69000, France
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Hôpital Foch
Suresnes, 92000, France
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Hôpital Henri Mondor
Créteil, 94000, France
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Hôpital Huriez
Lille, 59000, France
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Hôpital Necker
Paris, 75000, France
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Hôpital Pasteur
Nice, 06000, France
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Hôpital Pellegrin
Bordeaux, 33000, France
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Hôpital Rangueil
Toulouse, 31000, France
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Hôpital Saint-Louis
Paris, 75000, France
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Hôpital de Bois-Guillaume
Bois-Guillaume, 76000, France
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Hôpital de la Conception
Marseille, 13000, France
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Conditions
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