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Can a capsule reveal the Body's hidden Plant-Compound factory?

NCT ID NCT07772362

Knowledge-focused Sponsor: University of Ulster Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This study investigates how the body absorbs and processes (poly)phenols, natural compounds in plant foods that may lower the risk of heart and metabolic diseases. Researchers will give (poly)phenol-rich capsules to 20 adults with an ileostomy, a surgical opening that allows collection of small intestine contents. By analyzing these samples, they aim to see how much of these compounds are absorbed in the small intestine and how they are transformed, helping to explain why people respond differently to dietary (poly)phenols.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
(Poly)phenol-rich capsules (dietary supplement)
What this could lead to
This could help explain why people respond differently to plant-based diets, potentially leading to personalized nutrition advice for better heart and metabolic health.
What could go wrong
This is a small, early-stage study focused on understanding metabolism, not on treating a disease. Results may not apply to the general population, and individual responses could vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Currently living with an ileostomy * \> 1-year post-operative * Aged 18 - 75 years * BMI 18 - 28 kg/m2 * Males and females (not currently pregnant / lactating) * Non-smokers (including vaping) * Not taking antibiotic therapy 3 months prior to the study * No phytochemical supplement usage 2 weeks prior to study start. * Free-living (i.e. not housebound) * No participation in other biomedical studies 3 months prior. Exclusion Criteria: * Not currently living with an ileostomy * Ileostomy formed \< 1 year previously * Not aged 18 - 75 years * BMI \<18 or \>28 kg/m2 * Pregnant / lactating female * Smokers (including vaping) * Those taking antibiotic therapy 3 months prior to the study * Phytochemical supplement usage within 2 weeks of study start. * Housebound or otherwise unable to attend testing visits. * Participation in a biomedical study (3 months prior to study start).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ileostomy - stoma

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Ulster University, Human Intervention Studies Unit, Coleraine, Co. Londonderry, BT521SA

    RECRUITING

    Coleraine, United Kingdom

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