Could Gene-Tweaked leukemia cells fight cancer?

NCT ID NCT02483312

First seen Jan 02, 2026 · Last updated May 16, 2026 · Updated 20 times

Summary

This early-stage study tests a new approach for people with acute myeloid leukemia (AML) that has returned or is likely to return, and who cannot have a bone marrow transplant. Researchers take the patient's own leukemia cells, modify them in the lab to produce a protein called IL-12, and then give them back. The goal is to see if this treatment is safe and can help control the disease.

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Contacts and locations

Locations

  • Princess Margaret Centre Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.