New pill could ease rare lung disease

NCT ID NCT07365332

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called IKT-001 in people with pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes it hard to breathe and move. About 486 adults will receive either IKT-001 or a placebo to see if the drug improves blood flow and walking distance. The goal is to find a new way to manage PAH symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IKT-001 (tablet)

What this could lead to

If successful, this could provide a new treatment option to help control pulmonary arterial hypertension and improve daily function.

What could go wrong

This is a Phase 3 trial, but results are not guaranteed. The drug may not work better than placebo, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary arterial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Norton Healthcare

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States